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KMID : 0942820060050010059
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Journal of Korean Brain Tumor Society
2006 Volume.5 No. 1 p.59 ~ p.62
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Postradiation Osteosarcoma of the Frontal Bone
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Kang Hyoung-Lae
Shin Jun-Jae
Park Sang-Keun
Hwang Yong-Soon
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Abstract
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This is a case of a 21-year-old woman who was treated primitive neuroectodermal tumor(PNET) when she was 12-yearold. At that time, we performed radical surgery, radiation therapy, and chemotherapy. Forehead mass has developed after 11 years. On computed tomography, high density mass was detected on frontal bone and this lesion was removed by surgical operation. After surgery, chemotherapy was done at two times. The histological diagnosis was postradiation osteosarcoma. Postradiation osteosarcoma is a rare complication of radiation therapy. It has histologically been high-grade and poor prognosis. However, complete remission was obtained in our case after a couple of surgical operation, chemotherapy. This is the first case of postradiation osteosarcoma to be reported in the domestic. We treated a patient who developed osteosarcoma in the frontal bone 11 years after radiotherapy for PNET in the cerebellum and achieved favorable outcome.
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KEYWORD
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Radiation therapy, Postradiation osteosarcoma, Primitive neuroectodermal tumor(PNET)
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